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Positioning Early Phase CNS Trials for Regulatory and Investor Success: Strategic Implications of the Single Phase 3 Approval Paradigm

Positioning Early Phase CNS Trials for Regulatory and Investor Success: Strategic Implications of the Single Phase 3 Approval Paradigm

Publications

Abstract— In February 2026, the FDA announced that a single pivotal phase 3 (P3) trial would become the new default standard for drug approval—a regulatory direction that had been legally enabled since the FDA Modernization Act of 1997. This announcement has...
10 Lessons Learned Over 40 Years of Drug Development Research in Psychiatry

10 Lessons Learned Over 40 Years of Drug Development Research in Psychiatry

Publications

Sheldon Preskorn, MD, Senior Vice President of Neuroscience, presented “10 Lessons Learned Over 40 Years of Drug Development Research in Psychiatry” at the 2024 CNS Summit. Dr. Preskorn provided strategies for enhancing clinical trial design, minimizing patient...

Recent Posts

  • Positioning Early Phase CNS Trials for Regulatory and Investor Success: Strategic Implications of the Single Phase 3 Approval Paradigm
  • Dr. Vince Clinical Research Expands CRO Capabilities as William Lavery, MD, PhD, Earns Board Certification in Obesity Medicine
  • Full-Service CRO Overview
  • First-in-Human to Proof-of-Concept: The DVCR Continuity Model
  • The Hidden Risk in Early Development – Why Programs Lose Momentum

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