Primary and Secondary Outcomes From a Phase I Study Comparing the Respiratory Effects of Buprenorphine Buccal Film and Oral Oxycodone Hydrochloride Administration

Primary and Secondary Outcomes From a Phase I Study Comparing the Respiratory Effects of Buprenorphine Buccal Film and Oral Oxycodone Hydrochloride Administration

Lynn Webster, MD, Executive Vice President of Scientific Affairs, recently presented his poster titled “A Review of the Primary and Secondary Outcomes From a Phase I Study Comparing the Respiratory Effects of Buprenorphine Buccal Film and Oral Oxycodone Hydrochloride Administration.”

A phase 1 randomized, double-blind, placebo-controlled, double-dummy crossover study was conducted to compare the effects of Buprenorphine Buccal Film (BBF) and oxycodone immediate-release (IR). The study focused on respiratory drive, pharmacokinetics, oxygen saturation, and pupillary-constricting effects. The review covers previously published data from the study, which included healthy men and women who self-identified as recreational opioid users but were not currently dependent on opioids.

You can watch the presentation or read the article below.

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