Early phase certainty for your drug-drug interaction studies
DVCR helps sponsors execute drug-drug interaction studies with experienced clinical teams, pharmacy readiness, safety oversight, strong volunteer retention and technology-enabled data quality.
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Precision execution for complex DDI studies
Drug-drug interaction studies require coordination across pharmacy, dosing, safety monitoring, volunteer retention and data capture. DVCR supports sponsors with experienced DDI teams, an on-site cGMP compliant pharmacy and a purpose-built Phase I environment designed to support controlled study conduct.
DDI study experience
Experience conducting CYP enzyme and transporter-mediated interaction studies, pH-dependent interaction studies and cocktail approach DDI trials.
Probe and substrate sourcing
DVCR leverages multiple suppliers and preferred clinical trial supplier teams to support drug availability and lot consistency for required dosing.
Safety oversight
A dedicated ACLS-certified safety team is trained to identify, report and respond to adverse events and potential drug interactions.
Volunteer retention
A 100-bed Phase I unit with volunteer-centered amenities supports extended inpatient stays often required for DDI studies.
Technology-enabled data quality
Integrated systems support real-time data capture, sponsor visibility, audit-ready documentation and cleaner study conduct.
Pharmacy support for DDI execution
Procurement and preparation of probes, substrates and other study medications are critical to DDI execution. DVCR’s pharmacy team supports sourcing, preparation and handling across routes of administration, with experience in commonly used drugs such as midazolam, carbamazepine, rifampin, itraconazole, metformin, bupropion, rabeprazole and caffeine.
Key capabilities include:
- 50+ years of combined pharmacy research experience
- Procurement and preparation of FDA-recommended probes and substrates
- Use of multiple suppliers and preferred clinical trial supplier teams
- Lot consistency planning for required study dosing
- Handling across multiple routes of administration
- Injectable formulations, including IV, IM and subcutaneous
- Oral solutions
- Powder-in-capsule preparation
